V. Manda, J. Pavelka, and E. Lau. Proteomics applications in next generation induced pluripotent stem cell models. Expert Rev Proteomics, volume 21, issue 4, pages 217-228, April 2024. B. Pandi, S. Brenman, A. Black, D. C. M. Ng, E. Lau, and M. P. Y. Lam. Tissue Usage Preference and Intrinsically Disordered Region Remodeling of Alternative Splicing Derived Proteoforms in the Heart. J Proteome Res, March 2024. J. Currie, V. Manda, S. K. Robinson, C. Lai, V. Agnihotri, V. Hidalgo, R. W. Ludwig, K. Zhang, J. Pavelka, Z. V. Wang, J. W. Rhee, M. P. Y. Lam, and E. Lau. Simultaneous proteome localization and turnover analysis reveals spatiotemporal features of protein homeostasis disruptions. Nat Commun, volume 15, issue 1, pages 2207, March 2024. J. Pavelka and E. Lau. {A}ging models make waves: predicting vascular aging in virtual patients. Am J Physiol Heart Circ Physiol, volume 325, issue 6, pages H1264-H1265, December 2023. N. Kastury, V. Hidalgo, B. Pandi, L. Li, M. P. Y. Lam, and E. Lau. Senescence in human AC16 cardiac cells is associated with thymidine kinase induction and histone loss. MicroPubl Biol, volume 2023, June 2023. V. Hidalgo, N. Kastury, C. W. Durham, J. Currie, M. Amaya, M. P. Y. Lam, and E. Lau. Co-culture with normal and senescent AC16 cardiomyocytes modulates fibrotic response in primary human ventricular fibroblasts. MicroPubl Biol, volume 2023, June 2023. H. Srivastava, M. J. Lippincott, J. Currie, R. Canfield, M. P. Y. Lam, and E. Lau. Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners. PLoS Comput Biol, volume 18, issue 11, pages e1010702, November 2022. D. M. Eaton, R. M. Berretta, J. E. Lynch, J. G. Travers, R. D. Pfeiffer, M. L. Hulke, H. Zhao, A. R. H. Hobby, G. Schena, J. P. Johnson, M. Wallner, E. Lau, M. P. Y. Lam, K. C. Woulfe, N. R. Tucker, T. A. McKinsey, M. R. Wolfson, and S. R. Houser. Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF. Am J Physiol Heart Circ Physiol, volume 323, issue 4, pages H797-H817, October 2022. D. T. Paik, H. Kim, and E. Lau. Editorial: Intercellular communication and crosstalk in cardiac development and disease. Front Cardiovasc Med, volume 9, pages 1053539, October 2022. Y. Han, S. A. Wennersten, J. M. Wright, R. W. Ludwig, E. Lau, and M. P. Y. Lam. Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging. Am J Physiol Heart Circ Physiol, volume 323, issue 3, pages H538-H558, September 2022. D. E. Hammond, D. M. Simpson, C. Franco, M. W. Muelas, J. Waters, R. W. Ludwig, M. C. Prescott, J. L. Hurst, R. J. Beynon, and E. Lau. Harmonizing labeling and analytical strategies to obtain protein turnover rates in intact adult animals. Mol Cell Proteomics, volume 21, issue 7, pages 100252, July 2022. H. Srivastava, M. Pozzoli, and E. Lau. Defining the Roles of Cardiokines in Human Aging and Age-Associated Diseases. Front Aging, volume 3, pages 884321, April 2022. T. T. Wei, M. Chandy, M. Nishiga, A. Zhang, K. K. Kumar, D. Thomas, A. Manhas, S. Rhee, J. M. Justesen, I. Y. Chen, H. T. Wo, S. Khanamiri, J. Y. Yang, F. J. Seidl, N. Z. Burns, C. Liu, N. Sayed, J. J. Shie, C. F. Yeh, K. C. Yang, E. Lau, K. L. Lynch, M. Rivas, B. K. Kobilka, and J. C. Wu. Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. Cell, volume 185, issue 10, pages 1676-1693, April 2022. S. Veitch, M. S. Njock, M. Chandy, M. A. Siraj, L. Chi, H. Mak, K. Yu, K. Rathnakumar, C. A. Perez-Romero, Z. Chen, F. J. Alibhai, D. Gustafson, S. Raju, R. Wu, D. Z. Khat, Y. Wang, A. Caballero, P. Meagher, E. Lau, L. Pepic, H. S. Cheng, N. J. Galant, K. L. Howe, R. K. Li, K. A. Connelly, M. Husain, P. Delgado-Olguin, and J. E. Fish. MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes. Cardiovasc Diabetol, volume 21, issue 1, pages 31, February 2022. R. Ludwig and E. Lau. JCAST: Sample-specific protein isoform databases for mass spectrometry-based proteomics experiments. Software Impacts, volume 10, pages 100163, November 2021. Y. Han, L. Z. Li, N. L. Kastury, C. T. Thomas, M. P. Y. Lam, and E. Lau. Transcriptome features of striated muscle aging and predictability of protein level changes. Mol. Omics, The Royal Society of Chemistry, July 2021. K. C. Woulfe, D. A. Jeffrey, J. P. D. Silva, C. E. Wilson, J. H. Mahaffey, E. Lau, D. Slavov, F. Hailu, A. Karimpour-Fard, K. Dockstader, M. R. Bristow, B. L. Stauffer, S. D. Miyamoto, and C. C. Sucharov. Serum response factor deletion 5 regulates phospholamban phosphorylation and calcium uptake. J Mol Cell Cardiol, volume 159, pages 28-37, June 2021. T. Chour, L. Tian, E. Lau, D. Thomas, I. Itzhaki, O. Malak, J. Z. Zhang, X. Qin, M. Wardak, Y. Liu, M. Chandy, K. E. Black, M. P. Lam, E. Neofytou, and J. C. Wu. Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies. JCI Insight, volume 6, issue 7, April 2021. Y. Han, S. D. Wood, J. M. Wright, V. Dostal, E. Lau, and M. P. Y. Lam. Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart. J Mol Cell Cardiol, volume 154, pages 92-96, February 2021. V. Dostal, S. Wood, C. Thomas, Y. Han, E. Lau, and M. P. Lam. Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart. bioRxiv, 2020. M. Chandy, J. W. Rhee, M. O. Ozen, D. R. Williams, L. Pepic, C. Liu, H. Zhang, J. Malisa, E. Lau, U. Demirci, and J. C. Wu. Atlas of exosomal microRNAs secreted from human iPSC-derived cardiac cell types. Circulation, volume 142, issue 18, pages 1794-1796, November 2020. V. Dostal, S. D. Wood, C. T. Thomas, Y. Han, E. Lau, and M. P. Y. Lam. Proteomic signatures of acute oxidative stress response to paraquat in the mouse heart. Sci Rep, volume 10, issue 1, pages 18440, October 2020. J. X. Zhang, E. Lau, D. T. Paik, Y. Zhuge, and J. C. Wu. High-throughput preparation of DNA, RNA, and protein from cryopreserved human iPSCs for multi-omics analysis. Current protocols in stem cell biology, volume 54, issue 1, pages e114, September 2020. J.-W. Rhee, H. Yi, D. Thomas, C. K. Lam, N. Belbachir, L. Tian, X. Qin, J. Malisa, E. Lau, D. T. Paik, Y. Kim, B. S. Choi, N. Sayed, K. Sallam, R. Liao, and J. C. Wu. Modeling secondary iron overload cardiomyopathy with human induced pluripotent stem cell-derived cardiomyocytes. Cell reports, volume 32, issue 2, pages 107886, July 2020. E. Lau, Y. Han, D. R. Williams, C. T. Thomas, R. Shrestha, J. C. Wu, and M. P. Y. Lam. Splice-junction-based mapping of alternative isoforms in the human proteome. Cell reports, volume 29, issue 11, pages 3751—3765.e5, December 2019. J. Lee, V. Termglinchan, S. Diecke, I. Itzhaki, C. K. Lam, P. Garg, E. Lau, M. Greenhaw, T. Seeger, H. Wu, J. Z. Zhang, X. Chen, I. P. Gil, M. Ameen, K. Sallam, J.-W. Rhee, J. M. Churko, R. Chaudhary, T. Chour, P. J. Wang, M. P. Snyder, H. Y. Chang, I. Karakikes, and J. C. Wu. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature, volume 572, issue 7769, pages 335—340, August 2019. T. Seeger, R. Shrestha, C. K. Lam, C. Chen, W. L. McKeithan, E. Lau, A. Wnorowski, G. McMullen, M. Greenhaw, J. Lee, A. Oikonomopoulos, S. Lee, H. Yang, M. Mercola, M. Wheeler, E. A. Ashley, F. Yang, I. Karakikes, and J. C. Wu. A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Circulation, volume 139, issue 6, pages 799—811, February 2019. E. Lau, D. T. Paik, and J. C. Wu. Systems-Wide Approaches in Induced Pluripotent Stem Cell Models. Annual review of pathology, volume 14, pages 395—419, January 2019. E. Lau, V. Venkatraman, C. T. Thomas, J. C. Wu, J. E. V. Eyk, and M. P. Y. Lam. Identifying high-priority proteins across the human diseasome using semantic similarity. Journal of proteome research, volume 17, issue 12, pages 4267—4278, December 2018. E. Lau, V. Venkatraman, C. Thomas, J. V. Eyk, and M. P. Lam. Identifying high-priority proteins across the human diseasome using semantic similarity. bioRxiv, October 2018. E. Lau and J. C. Wu. Omics, big data, and precision medicine in cardiovascular sciences. Circulation research, volume 122, issue 9, pages 1165—1168, April 2018. A. S. Lee, M. Inayathullah, M. A. Lijkwan, X. Zhao, W. Sun, S. Park, W. X. Hong, M. B. Parekh, A. V. Malkovskiy, E. Lau, X. Qin, V. R. Pothineni, V. Sanchez-Freire, W. Y. Zhang, N. G. Kooreman, A. D. Ebert, C. K. F. Chan, P. K. Nguyen, J. Rajadas, and J. C. Wu. Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptides from a collagen matrix. Nature biomedical engineering, volume 2, issue 2, pages 104—113, February 2018. F. Olmeta-Schult, L. M. Segal, S. Tyner, T. A. Moon, R. D.-W. Chow, P. Chakrabarty, M. Pacesa, A. I. Podgornaia, J. Chen, B. Singh, B. Cao, R. R. S. Sidhu, B. W. Q. Tan, P. Sood, S. Parker, M. A. Scult, D. V. Haute, N. Konstantinides, B. A. Schwendimann, S. Srivastava, R. Fiorenza, K. Dutton-Regester, R. Hale, E. O. Polat, E. Lau, A. L. Mayer, and E. R. White. NextGen VOICES: Research resolutions. Science (New York, N.Y.), volume 359, issue 6371, pages 26—28, January 2018. E. Lau, Q. Cao, M. P. Y. Lam, J. Wang, D. C. M. Ng, B. J. Bleakley, J. M. Lee, D. A. Liem, D. Wang, H. Hermjakob, and P. Ping. Integrated Omics Dissection of Proteome Dynamics During Cardiac Remodeling. Nature communications, volume 9, issue 1, pages 120, January 2018. M. P. Y. Lam, E. Lau, D. C. M. Ng, D. Wang, and P. Ping. Cardiovascular proteomics in the era of big data: experimental and computational advances. Clinical proteomics, volume 13, pages 23, December 2016. M. P. Y. Lam, V. Venkatraman, Y. Xing, E. Lau, Q. Cao, D. C. M. Ng, A. I. Su, J. Ge, J. E. V. Eyk, and P. Ping. Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems. Journal of proteome research, volume 15, issue 11, pages 4126—4134, November 2016. E. Lau, K. E. Watson, and P. Ping. Connecting the Dots: From Big Data to Healthy Heart. Circulation, volume 134, issue 5, pages 362—364, August 2016. A. Gramolini, E. Lau, and P. P. Liu. Identifying Low-Abundance Biomarkers: Aptamer-Based Proteomics Potentially Enables More Sensitive Detection in Cardiovascular Diseases. Circulation, volume 134, issue 4, pages 286—289, July 2016. E. Lau, Q. Cao, D. C. M. Ng, B. J. Bleakley, T. U. Dincer, B. M. Bot, D. Wang, D. A. Liem, M. P. Y. Lam, J. Ge, and P. Ping. A large dataset of protein dynamics in the mammalian heart proteome. Scientific data, volume 3, pages 160015, March 2016. M. Kudelko, C. W. L. Chan, R. Sharma, Q. Yao, E. Lau, I. K. Chu, K. S. E. Cheah, J. A. Tanner, and D. Chan. Label-Free Quantitative Proteomics Reveals Survival Mechanisms Developed by Hypertrophic Chondrocytes under ER Stress. Journal of proteome research, volume 15, issue 1, pages 86—99, January 2016. M. P. Y. Lam, V. Venkatraman, Q. Cao, D. Wang, T. U. Dincer, E. Lau, A. I. Su, Y. Xing, J. Ge, P. Ping, and J. E. V. Eyk. Prioritizing Proteomics Assay Development for Clinical Translation. Journal of the American College of Cardiology, volume 66, issue 2, pages 202—204, July 2015. E. Lau, D. Huang, Q. Cao, T. U. Dincer, C. M. Black, A. J. Lin, J. M. Lee, D. Wang, D. A. Liem, M. P. Y. Lam, and P. Ping. Spatial and temporal dynamics of the cardiac mitochondrial proteome. Expert review of proteomics, volume 12, issue 2, pages 133—146, April 2015. X. C. Y. Chan, C. M. Black, A. J. Lin, P. Ping, and E. Lau. Mitochondrial protein turnover: methods to measure turnover rates on a large scale. Journal of molecular and cellular cardiology, volume 78, pages 54—61, January 2015. D. Wang, D. A. Liem, E. Lau, D. C. M. Ng, B. J. Bleakley, M. Cadeiras, M. C. Deng, M. P. Y. Lam, and P. Ping. Characterization of human plasma proteome dynamics using deuterium oxide. Proteomics. Clinical applications, volume 8, issue 78, pages 610—619, August 2014. N. Zong, P. Ping, E. Lau, H. J. Choi, D. C. Ng, D. Meyer, C. Fang, H. Li, D. Wang, I. M. Zelaya, J. R. Yates, and M. P. Lam. Lysine ubiquitination and acetylation of human cardiac 20S proteasomes. Proteomics. Clinical applications, volume 8, issue 78, pages 590—594, August 2014. M. P. Y. Lam, D. Wang, E. Lau, D. A. Liem, A. K. Kim, D. C. M. Ng, X. Liang, B. J. Bleakley, C. Liu, J. D. Tabaraki, M. Cadeiras, Y. Wang, M. C. Deng, and P. Ping. Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. The Journal of clinical investigation, volume 124, issue 4, pages 1734—1744, April 2014. C. Lotz, A. J. Lin, C. M. Black, J. Zhang, E. Lau, N. Deng, Y. Wang, N. C. Zong, J. H. Choi, T. Xu, D. A. Liem, P. Korge, J. N. Weiss, H. Hermjakob, J. R. Yates, R. Apweiler, and P. Ping. Characterization, design, and function of the mitochondrial proteome: from organs to organisms. Journal of proteome research, volume 13, issue 2, pages 433—446, February 2014. M. P. Y. Lam, E. Lau, D. A. Liem, and P. Ping. Cyclophilin D and acetylation: a new link in cardiac signaling. Circulation research, volume 113, issue 12, pages 1268—1269, December 2013. L. J. Martin, E. Lau, H. Singh, L. Vergnes, E. J. Tarling, M. Mehrabian, I. Mungrue, S. Xiao, D. Shih, L. Castellani, P. Ping, K. Reue, E. Stefani, T. A. Drake, K. Bostrom, and A. J. Lusis. Response to Pomozi et al's research commentary. Circulation research, volume 112, issue 11, pages e152—3, May 2013. M. P. Y. Lam, E. Lau, S. B. Scruggs, D. Wang, T.-Y. Kim, D. A. Liem, J. Zhang, C. M. Ryan, K. F. Faull, and P. Ping. Site-specific quantitative analysis of cardiac mitochondrial protein phosphorylation. Journal of proteomics, volume 81, pages 15—23, April 2013. T.-Y. Kim, D. Wang, A. K. Kim, E. Lau, A. J. Lin, D. A. Liem, J. Zhang, N. C. Zong, M. P. Y. Lam, and P. Ping. Metabolic labeling reveals proteome dynamics of mouse mitochondria. Molecular & cellular proteomics : MCP, volume 11, issue 12, pages 1586—1594, December 2012. M. P. Y. Lam, S. B. Scruggs, T.-Y. Kim, C. Zong, E. Lau, D. Wang, C. M. Ryan, K. F. Faull, and P. Ping. An MRM-based workflow for quantifying cardiac mitochondrial protein phosphorylation in murine and human tissue. Journal of proteomics, volume 75, issue 15, pages 4602—4609, August 2012. L. J. Martin, E. Lau, H. Singh, L. Vergnes, E. J. Tarling, M. Mehrabian, I. Mungrue, S. Xiao, D. Shih, L. Castellani, P. Ping, K. Reue, E. Stefani, T. A. Drake, K. Bostrom, and A. J. Lusis. ABCC6 localizes to the mitochondria-associated membrane. Circulation research, volume 111, issue 5, pages 516—520, August 2012. J. Zhang, A. Lin, J. Powers, M. P. Lam, C. Lotz, D. Liem, E. Lau, D. Wang, N. Deng, P. Korge, N. C. Zong, H. Cai, J. Weiss, and P. Ping. Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondrial proteome design: from molecular identity to pathophysiological regulation. The Journal of general physiology, volume 139, issue 6, pages 395—406, June 2012. E. Lau, D. Wang, J. Zhang, H. Yu, M. P. Y. Lam, X. Liang, N. Zong, T.-Y. Kim, and P. Ping. Substrate- and isoform-specific proteome stability in normal and stressed cardiac mitochondria. Circulation research, volume 110, issue 9, pages 1174—1178, April 2012. M. P. Y. Lam, E. Lau, S. Siu, D. C. M. Ng, R. P. W. Kong, P. C. N. Chiu, W. S. B. Yeung, C. Lo, and I. K. Chu. Online combination of reversed-phase/reversed-phase and porous graphitic carbon liquid chromatography for multicomponent separation of proteomics and glycoproteomics samples. Electrophoresis, volume 32, issue 21, pages 2930—2940, November 2011. S. Siu, M. P. Y. Lam, E. Lau, R. P. W. Kong, S. M. Y. Lee, and I. K. Chu. Fully automatable two-dimensional reversed-phase capillary liquid chromatography with online tandem mass spectrometry for shotgun proteomics. Proteomics, volume 11, issue 11, pages 2308—2319, June 2011. E. Lau, M. P. Y. Lam, S. Siu, R. P. W. Kong, W. L. Chan, Z. Zhou, J. Huang, C. Lo, and I. K. Chu. Combinatorial use of offline SCX and online RP-RP liquid chromatography for iTRAQ-based quantitative proteomics applications. Molecular bioSystems, volume 7, issue 5, pages 1399—1408, May 2011. M. P. Y. Lam, S. Siu, E. Lau, X. Mao, H. Sun, P. C. N. Chiu, W. S. B. Yeung, D. M. Cox, and I. K. Chu. Online coupling of reverse-phase and hydrophilic interaction liquid chromatography for protein and glycoprotein characterization. Analytical and bioanalytical chemistry, volume 398, issue 2, pages 791—804, September 2010. H. Liu, E. Lau, M. P. Y. Lam, H. Chu, S. Li, G. Huang, P. Guo, J. Wang, L. Jiang, I. K. Chu, C. Lo, and Y. Tao. OsNOA1/RIF1 is a functional homolog of AtNOA1/RIF1: implication for a highly conserved plant cGTPase essential for chloroplast function. The New phytologist, volume 187, issue 1, pages 83—105, July 2010. S. Siu, M. P. Y. Lam, E. Lau, W. S. B. Yeung, D. M. Cox, and I. K. Chu. N-linked glycoprotein analysis using dual-extraction ultrahigh-performance liquid chromatography and electrospray tandem mass spectrometry. Methods in molecular biology (Clifton, N.J.), volume 600, pages 133—143, September 2009.